Heterozygote advantage for the phenylketonuria allele.

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Heterozygote advantage for the phenylketonuria allele.

Mean weight at birth of unaffected (normal homozygous and PKU heterozygous) offspring of parents heterozygous for the phenylketonuria (PKU) allele averages significantly above that of Norwegian neonates, with no significant difference in mean age of mothers or in mean parity. It approaches the optimal birthweight--that which confers the minimum overall mortality in the pre-, peri-, and postnata...

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ژورنال

عنوان ژورنال: Journal of Medical Genetics

سال: 1978

ISSN: 1468-6244

DOI: 10.1136/jmg.15.4.317-a